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Description

PIE appears as red or pink marks caused by damaged blood vessels, while PIH appears as brown or grey marks caused by excess melanin

Am J Hum Genet 73 (2): 301-13, 2003

Myristoylation of TRAM targets it to the plasma membrane, where it is essential for the LPS-induced release of inflammatory mediators and cytokines through the TLR4 signaling